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Best Options Strategy for PCVX

By Yojana Mandon · Updated 2026-08-14 · 2 min read · Risk disclaimer

Looking for the best options strategy for Vaxcyte, Inc. (PCVX)? There is no single answer — the right play depends on your outlook, your risk tolerance and current implied volatility. Below, our free engine shows the highest-scoring defined-risk strategy on the live PCVX option chain right now, and a simple map from your view on PCVX to the strategy that fits it. Model any of them in the calculator before you trade.

About PCVX

Vaxcyte, Inc. (PCVX) is a major company in Biotechnology. Options traders on PCVX tend to watch , since these can drive large moves in the share price.

About Vaxcyte, Inc.

Vaxcyte develops vaccines aimed at preventing or treating bacterial infections, primarily focusing on pneumococcal disease and related conditions. The company's core pipeline centers on pneumococcal conjugate vaccines (PCVs) designed using a carrier-sparing technology platform. Its most advanced candidate, VAX-24, targets invasive pneumococcal disease in infants and covers 24 serotypes, while VAX-31 extends to 31 serotypes for older populations. Beyond pneumococcal work, Vaxcyte is advancing VAX-A1 for Group A Streptococcus prevention, VAX-PG as a protein vaccine against periodontitis, and VAX-GI for Shigella-caused dysentery. The company also has a third-generation pneumococcal vaccine in development called VAX-XL. Founded in 2013 and based in San Carlos, California, Vaxcyte was previously known as SutroVax before rebranding in 2020.

As a clinical-stage biotech company, Vaxcyte does not currently generate revenue from product sales. The company operates in the global vaccine market, which includes both infant immunization programs and adult preventive health segments. Its financial model depends on advancing candidates through clinical trials, securing partnerships or licensing…

Today's top-scoring strategy for PCVX

Our engine ranks defined-risk strategies on the live PCVX chain by probability of profit and risk/reward, then surfaces the best-scoring one. It is an educational illustration, not advice.

Iron Butterfly neutral
Price: $58.03Implied volatility: 57%Expiration: 2026-09-18 (34d)
ActionQtyTypeStrikePremium
BuyPUT$40$0.65
SellPUT$60$4.35
SellCALL$60$2.38
BuyCALL$65$0.93
P/L at expiry vs today At expiry Today ±1σ
$25$53$80
Max Profit
$508
Max Loss
−$1,485
Net Credit (received)
$515
Breakeven(s)
$54.85
Position Greeks
Δ
35.63
Γ
−4.112
Θ
6.20
ν
−7.43
Time decay (price held)
Implied-volatility skew

Simulation

Forward simulation of 6,000 lognormal price paths to expiration — not a historical backtest.

Win rate
60%
Mean P/L
−$146
Median
$15
Exp. move (1σ)
18%
5th pct
−$1,166
25th pct
−$413
75th pct
$172
95th pct
$443

Strategy analysis

Simulated price paths (time × price)
now $58BE $55$43$60$760d17d34d
$-1461$-485$491

Greeks vs price

Δ — $ P/L per $1 move in the underlying (share-equivalent exposure).
Θ — $ P/L per day from time decay.
ν — $ P/L per +1% in implied volatility.
Γ — how fast delta changes per $1 move.

Price × volatility (today)

−30%−15%IV+15%+30%
$73$58$58$46$24−$5
$70$77$65$41$8−$29
$67$93$63$25−$18−$64
$64$94$44−$8−$61−$113
$61$65−$1−$64−$124−$180
$58−$11−$84−$151−$212−$266
$55−$145−$211−$272−$326−$375
$52−$337−$383−$427−$468−$504
$49−$571−$589−$610−$631−$651
$46−$822−$813−$808−$807−$809
$44−$1,060−$1,030−$1,004−$984−$969
Analyze PCVX in the calculator → Share this pick ↗

Live scan from 2026-08-14 · quotes delayed ~15 minutes

Historical backtest: how a Iron Butterfly on PCVX would have performed

We approximated a Iron Butterfly on PCVX, entered repeatedly over the past year (92 historical entries, each held to expiration) with Black-Scholes-modelled entry premiums. Here is how that would have played out on real PCVX price history — an educational backtest, not a prediction of future returns.

Trades
92
Win rate
53%
Total P/L
$4,724
Avg return on risk
+38%
Best trade
$841
Worst trade
-$663
Cumulative P/L over the backtest

Approximate: entry premiums are modelled with Black-Scholes from trailing realised volatility, held to expiration and settled against the real historical close. Real fills, implied volatility and slippage differ — treat it as directional context, not exact returns.

Implied volatility

PCVX is currently trading with high implied volatility, which makes its options expensive — and attractive to sell. On the options we scanned that was around 57% implied volatility, and higher implied volatility means richer premiums and wider expected moves.

Options on PCVX currently price in about 57% implied volatility, versus roughly 43% the stock has actually realised over the past month. That makes options relatively expensive — an edge for strategies that sell premium, such as credit spreads and iron condors.

PCVX's IV Rank is 27/100: implied volatility sits 27% of the way between its 17-day low (53%) and high (69%), and is above 39% of recorded days. Premium is historically cheap, which favours net-debit strategies like long options and debit spreads.

Off that volatility, the options market is pricing a move of about ±$10.17 (±18%) in PCVX by 2026-09-18 — a range of roughly $47.86 to $68.2. Strikes inside that band hold most of the premium and see most of the action.

Across strikes, downside puts on PCVX trade at a higher implied volatility than upside calls — the market is paying up for crash protection. That skew favours selling put spreads or buying calls over symmetric trades.

PCVX options chain highlights: open interest, volume and skew

The live PCVX options chain shows a put/call open-interest ratio of 1.14 (balanced), with at-the-money implied volatility near 46.2%. Open interest clusters at the $65 call — a common resistance "wall" — and the $55 put, a support "wall": the strikes option writers are most exposed to into expiration.

Put/Call OI
1.14
Put/Call volume
0.8
ATM IV
46.2%
Put–call IV skew
+7.4
Call OI wall
$65 · 5
Put OI wall
$55 · 300
Most active call
$55 · 2
Most active put
$60 · 4
Most active strikes (volume)
$40$55$65
Calls   Puts

Snapshot of open interest, volume and implied volatility for the nearest scanned expiration — context, not a trading signal.

PCVX insider trading activity (SEC Form 4)

Open-market insider transactions at PCVX over roughly the last six months, from SEC Form 4 filings. Open-market buys are the rarer, more telling signal — routine selling under pre-arranged plans is common, so read a net-selling figure with that in mind.

Open-market buys
0 · —
Open-market sells
41 · $7.7M
Net (buy − sell)
−$7.7M
InsiderActionSharesValueDate
Dhaliwal Harpreet S.Sell17,000$935K2026-08-05
Wassil JimSell1,389$75K2026-08-03
Wassil JimSell861$46K2026-08-03
GUGGENHIME ANDREWSell3,044$165K2026-08-03
GUGGENHIME ANDREWSell6,956$374K2026-08-03
PICKERING GRANTSell378$21K2026-07-27

Source: SEC Form 4 filings via Finnhub. Open-market purchases (P) and sales (S) only — grants, option exercises, gifts and tax withholding are excluded. Informational context, not investment advice.

Liquidity and tradeability

PCVX options are thinly traded, with wide bid-ask spreads around 8.7% near the money that eat into any edge — favour simple single-leg or tight defined-risk trades, and always use limit orders.

Earnings & IV crush

PCVX's next earnings report is due around November 3, 2026. Options that expire after it price in a binary move, so their implied volatility is elevated and usually collapses right after the announcement — an "IV crush". If your expiration falls before this date, the trade sidesteps the event.

Key figures

Market cap
$8.0B
Beta (vs market)
1.21
52-week range
$29.08–$65.00 (81% up the range)
Short interest
9.9% of float · 7.7 days to cover

How to choose an options strategy for PCVX

Start with your outlook on PCVX, then match it to a defined-risk structure. Here are the most common choices and when each makes sense:

Bullish

You expect PCVX to rise

Buy a call for leverage with capped risk, or a bull call spread to lower the cost and breakeven when you have a target price.

Long Call → Bull Call Spread →

Bearish

You expect PCVX to fall

Buy a put to profit from a decline with defined risk, or a bear put spread to cheapen the trade when you expect a measured move down.

Long Put → Bear Put Spread →

Neutral

You expect PCVX to trade in a range

Sell an iron condor to collect premium while PCVX stays between two strikes, or write a covered call against shares you already own.

Iron Condor → Covered Call →

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How we pick the best strategy

For each ticker we pull the live option chain, build every supported strategy around the at-the-money strikes, and score them on probability of profit, risk/reward and capital efficiency — favouring defined-risk structures where the maximum loss is known up front. Methodology →

Open PCVX in the free calculator →

Frequently asked questions

What is the best options strategy for PCVX?

It depends on your outlook. Bullish traders often use a long call or bull call spread on PCVX; bearish traders a long put or bear put spread; neutral traders an iron condor or covered call. Our live scan above shows the current highest-scoring defined-risk play.

Are PCVX options liquid enough to trade?

Vaxcyte, Inc. (PCVX) is among the most actively-traded US options, which usually means tight bid/ask spreads and plenty of strikes and expirations — though you should always check the open interest and spread on the exact contract.

How much money do I need to trade PCVX options?

Buying a single PCVX call or put can cost as little as the premium (often one to a few hundred dollars), while income strategies like a cash-secured put need enough capital to buy 100 shares if assigned.

Is this financial advice?

No. Everything here is educational and uses delayed, third-party data. It is not a recommendation to trade PCVX or any security. Do your own research.

What does Vaxcyte, Inc. do?

Vaxcyte, Inc. (PCVX) operates in the Biotechnology industry. The "About Vaxcyte, Inc." section above gives a fuller picture of what the company does and how it earns money.

Does Vaxcyte, Inc. pay a dividend?

We don't show a confirmed dividend yield for Vaxcyte, Inc. here, so treat it as uncertain: before writing calls, check its current dividend and ex-dividend date with your broker — an approaching ex-dividend date can trigger early assignment on in-the-money short calls.

When does Vaxcyte, Inc. next report earnings?

Vaxcyte, Inc.'s next earnings are expected around November 3, 2026. Implied volatility usually climbs into the report and drops sharply afterwards (IV crush) — important for any options position held over the date.

Price trend

Short term · 1M
▲ +3.6%
Mid term · 3M
▲ +8.5%
Long term · 1Y
▲ +77.6%

Tickers related to PCVX

Comparing PCVX with similar names can help you choose the best options strategy:

NUVLNuvalent, Inc.KYMRKymera Therapeutics, Inc.LEGNLegend Biotech CorporationCRNXCrinetics Pharmaceuticals, Inc.

Company information

Headquarters
825 Industrial Road, Suite 300, San Carlos, CA, 94070, United States
Industry
Biotechnology
Employees
507
CEO
Mr. Grant E. Pickering M.B.A.
Phone
650 837 0111
Website
vaxcyte.com

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