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Best Options Strategy for ANNX

By Yojana Mandon · Updated 2026 · 2 min read · Risk disclaimer

Looking for the best options strategy for Annexon, Inc. (ANNX)? There is no single answer — the right play depends on your outlook, your risk tolerance and current implied volatility. Below, our free engine shows the highest-scoring defined-risk strategy on the live ANNX option chain right now, and a simple map from your view on ANNX to the strategy that fits it. Model any of them in the calculator before you trade.

About ANNX

Annexon, Inc. (ANNX) is a major company in Biotechnology. Options traders on ANNX tend to watch , since these can drive large moves in the share price.

About Annexon, Inc.

Annexon is a clinical-stage biotech firm focused on developing medicines for inflammatory and neurological diseases. The company's lead candidate, Tanruprubart, is a monoclonal antibody currently in Phase 3 testing for Guillain-Barré syndrome, while earlier-stage trials are underway for Huntington's disease and amyotrophic lateral sclerosis. Beyond Tanruprubart, the pipeline includes ANX007, a smaller antibody fragment in Phase 3 development for geographic atrophy, ANX1502, an oral small molecule in Phase 1 trials for autoimmune conditions, and ANX009, a C1q-blocking antibody fragment in Phase 1 studies for lupus nephritis. Founded in 2011 and based in Brisbane, California, the company operates primarily on development of its proprietary drug candidates.

As a clinical-stage company with no approved products on the market, Annexon generates revenue through research collaborations, grant funding, and potentially milestone or licensing arrangements rather than product sales. The firm's financial model depends on advancing its pipeline through clinical trials while managing development costs. Its addressable market encompasses relatively rare neurological and autoimmune diseases,…

Today's top-scoring strategy for ANNX

Our engine ranks defined-risk strategies on the live ANNX chain by probability of profit and risk/reward, then surfaces the best-scoring one. It is an educational illustration, not advice.

Long Call Butterfly neutral
Price: $100.00Implied volatility: 32%Expiration: 2026-07-17 (30d)
ActionQtyTypeStrikePremium
BuyCALL$95$6.83
SellCALL$100$3.82
BuyCALL$105$1.87
P/L at expiry vs today At expiry Today ±1σ
$82$100$118
Max Profit
$394
Max Loss
−$106
Net Debit (cost)
$106
Prob. of Profit
33%
Breakeven(s)
$96.06, $103.94
Implied Vol (ATM)
32%
Position Greeks
Δ
0.43
Γ
−1.202
Θ
1.69
ν
−3.16
Time decay (price held)

Simulation

Forward simulation of 6,000 lognormal price paths to expiration — not a historical backtest.

Win rate
33%
Mean P/L
−$2
Median
−$106
Exp. move (1σ)
9%
5th pct
−$106
25th pct
−$106
75th pct
$96
95th pct
$333
$-100$144$388
Analyze ANNX in the calculator → Share this pick ↗

Illustrative example at ANNX's latest available price, computed with the same engine as the tool. Live option fills and the real IV skew refresh during US market hours.

Implied volatility

ANNX typically trades with moderate implied volatility, broadly in line with other large-cap stocks. Implied volatility drives option prices, so it is worth checking the live chain before you trade.

Key figures

Market cap
$895M
Beta (vs market)
1.18
52-week range
$1.85–$7.18
Short interest
17.2% of float · 9.6 days to cover

With 17.2% of ANNX's float sold short, squeeze and gap risk are elevated — one reason its options can stay expensive.

How to choose an options strategy for ANNX

Start with your outlook on ANNX, then match it to a defined-risk structure. Here are the most common choices and when each makes sense:

Bullish

You expect ANNX to rise

Buy a call for leverage with capped risk, or a bull call spread to lower the cost and breakeven when you have a target price.

Long Call → Bull Call Spread →

Bearish

You expect ANNX to fall

Buy a put to profit from a decline with defined risk, or a bear put spread to cheapen the trade when you expect a measured move down.

Long Put → Bear Put Spread →

Neutral

You expect ANNX to trade in a range

Sell an iron condor to collect premium while ANNX stays between two strikes, or write a covered call against shares you already own.

Iron Condor → Covered Call →

How we pick the best strategy

For each ticker we pull the live option chain, build every supported strategy around the at-the-money strikes, and score them on probability of profit, risk/reward and capital efficiency — favouring defined-risk structures where the maximum loss is known up front. Methodology →

Open ANNX in the free calculator →

Frequently asked questions

What is the best options strategy for ANNX?

It depends on your outlook. Bullish traders often use a long call or bull call spread on ANNX; bearish traders a long put or bear put spread; neutral traders an iron condor or covered call. Our live scan above shows the current highest-scoring defined-risk play.

Are ANNX options liquid enough to trade?

Annexon, Inc. (ANNX) is among the most actively-traded US options, which usually means tight bid/ask spreads and plenty of strikes and expirations — though you should always check the open interest and spread on the exact contract.

How much money do I need to trade ANNX options?

Buying a single ANNX call or put can cost as little as the premium (often one to a few hundred dollars), while income strategies like a cash-secured put need enough capital to buy 100 shares if assigned.

Is this financial advice?

No. Everything here is educational and uses delayed, third-party data. It is not a recommendation to trade ANNX or any security. Do your own research.

What does Annexon, Inc. do?

Annexon, Inc. (ANNX) operates in the Biotechnology industry. The "About Annexon, Inc." section above gives a fuller picture of what the company does and how it earns money.

Does Annexon, Inc. pay a dividend?

Annexon, Inc. does not currently pay a dividend, so there is no ex-dividend assignment risk to plan around for options strategies.

Tickers related to ANNX

Comparing ANNX with similar names can help you choose the best options strategy:

FDMT4D Molecular Therapeutics, Inc.CCCCC4 Therapeutics, Inc.

Company information

Headquarters
1400 Sierra Point Parkway, Building C Suite 200, Brisbane, CA, 94005, United States
Industry
Biotechnology
Employees
93
Phone
650 822 5500
Website
www.annexonbio.com

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